Table 3

Chronic and acute white matter lesion volumes as predictors for APP metabolites in all patients.

Dependent Variables

Independent variables p (beta)


cWML

aWML

Age


CSF sAPP-α

≤0.005

n.s.

n.s.

(-0.396)


CSF sAPP-β

≤0.01

n.s.

n.s.

(-0.369)


CSF AβX-38

≤0.01

n.s.

≤0.01

(-0.359)

(0.371)


CSF AβX-40

≤0.05

n.s.

≤0.05

(-0.357)

(0.309)


CSF AβX-42

≤0.05

n.s.

n.s.

(-0.273)


Chronic WML significantly predicts CSF levels of APP metabolites.

cWML = chronic WML, aWML = acute WML.

Selnes et al. Cerebrospinal Fluid Research 2010 7:10   doi:10.1186/1743-8454-7-10

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